Mitochondrial tRNA mutations in Chinese children with tic disorders
نویسندگان
چکیده
منابع مشابه
Pollakiuria in children with tic disorders.
BACKGROUND To describe the rarely reported characteristics of pollakiuria in children with tic disorders (TD). METHODS During a period of one year, all patients visiting our Tourette Syndrome (TS) Clinic with TD were studied for presentation of pollakiuria. RESULTS We found that nine (1.9%) out of 467 children with TD had pollakiuria: 407 boys and 60 girls, with a mean age of 8.7 years. Of ...
متن کاملChronic tic disorders in children with ADHD.
OBJECTIVE To examine in a community-based cohort: (1) the prevalence of chronic tic disorder (CTD) in children with attention-deficit/hyperactivity disorder (ADHD) compared with non-ADHD controls at ages 7 and 10; and (2) the additional psychiatric and functional burden of CTD in children with ADHD. METHODS Children aged 6-8 years with ADHD (n=179) and controls (n=212) were recruited through ...
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A considerable body of evidence supports the role of mitochondrial dysfunction in psychiatric disorders and mitochondrial DNA (mtDNA) mutations are known to alter brain energy metabolism, neurotransmission, and cause neurodegenerative disorders. Genetic studies focusing on common nuclear genome variants associated with these disorders have produced genome wide significant results but those stud...
متن کاملVariables Associated With Tic Exacerbation in Children With Chronic Tic Disorders.
Research has shown that motor and vocal tics fluctuate in frequency, intensity, and form in response to environmental and contextual cues. Behavioral models have proposed that some of the variation in tics may reflect context-dependent interactive learning processes such that once tics are performed, they are influenced by environmental contingencies. The current study describes the results of ...
متن کاملMitochondrial tRNA mutations in patients with myelodysplastic syndromes.
Increasing evidence showed that mitochondria play an important role in the development of myelodysplastic syndromes (MDS). Mitochondrial dysfunctions caused by mitochondrial DNA mutations, especially mitochondrial tRNA mutations, were found to be associated with MDS in many studies. However, the link between a candidate mitochondrial tRNA mutation and MDS was not clear. In this study, we invest...
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ژورنال
عنوان ژورنال: Bioscience Reports
سال: 2020
ISSN: 0144-8463,1573-4935
DOI: 10.1042/bsr20201856